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One-stop Technology Platform to Accelerate Drug Discovery and Development

  1. Capabilities
  2. Non-GLP Repeated-dose Toxicology

Non-GLP Repeated-dose Toxicology

Repeated dose toxicity study is to characterize the adverse toxicological effects occurring as a result of repeated dosing with a substance to the test species. Effects include changes in morphology, physiology, life span, clinical chemistry and behavior. The studies can provide information including the toxicity to specific target organs, the dose-response relationship and reversibility/irreversibility of the effect.

Our non-GLP repeated dose toxicity study can be conducted in the early phase of drug development, which helps to guide the optimization of compound and has great impact on the success of a drug discovery program.

We can conduct toxicity study on mice and rats, our capability including the following:

  • Clinical observation

  • Hematology

  • Clinical chemistry

  • Gross pathology

  • Body and organ weights measurement

  • Histopathology

  • Toxicokinetics

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