Welcome to HitGen

Therapeutic Areas

Integrated One-stop Drug Discovery Platform   Accelerating Project with High Efficiency

  1. Therapeutic Areas
  2. Infectious Diseases

Infectious Diseases

Infectious diseases still remain to be one of the biggest global public health concerns. Virus infection and antibiotic resistance are the serious, worldwide threat to public health. 

HitGen team have expertise in anti-infectives discovery and development, and can provide integrated anti-infectives discovery programs by using cutting edge technologies such as protein degradation, siRNA and covalent DEL screening. 

Services for infectious diseases drug discovery and development:

  • Target proposal

  • Recombinant target protein production

  • Biochemical assays dvelopment

  • Structure based design

  • Screening and lead identification

  • in vitro bacterial efficacy (such as MIC50/MIC90/ MBC/ PAE) 

  • Cytopathic effect (CPE) screen

  • in vivo bacterial or fungal efficacy 

  • Drug metabolism and pharmacokinetics (DMPK) 

  • Safety

  • IND submission

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